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Faculty of Agriculture researcher partners in the fight against COVID‑19

- June 9, 2020

Bruce Rathgeber of the Dal-hosted Atlantic Poultry Research Institute. (File photo)
Bruce Rathgeber of the Dal-hosted Atlantic Poultry Research Institute. (File photo)

The Atlantic Poultry Research Centre on the »ÆÉ«Ö±²¥ Agricultural Campus has partnered with AffinityImmuno Inc, in Prince Edward Island, one of the first laboratories to manufacture antibodies against COVID-19.

Following successful production of antibodies in chickens to COVID-19 spike proteins, a partner was needed who had the capacity to increase the number of chickens involved in the process in order to scale-up production.  This is where the Faculty of Agriculture stepped in.

“The initial goal was to involve 100 hens for this research,� explains Associate Professor Bruce Rathgeber. “A high demand for COVID-19 spike protein has left us short. We currently have 51 birds and are still planning to have a group of 49 to bring it up to 100 once more protein becomes available.�

The Faculty of Agriculture will send eggs from the injected chickens to AffinityImmuno Inc., who will be harvestingantibodies from the yolks. The antibodies will be evaluated for a manufacturing effort toward the development of a simple-to-use diagnostic device to test for the virus as well as whether someone has been exposed and developed their own immunity.

“Antibodies against COVID-19 can be useful for a number of applications in the fight to control this disease,� says Dr. Rathgeber. “So far we have given our birds two doses of the material and we are closely monitoring their health.�

There is no risk the chickens will become sick from the COVID-19 spike protein as it is only a virus protein and not the complete virus. Additionally, there is no evidence that this virus is active in birds.